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ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will raise the degree or outcome of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Acute ergot toxicity characterised by vasospasm and tissue ischemia has been linked to coadministration of ritonavirHeadache, intermittent claudication, muscle mass pains, numb

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